At MUMC (Maastricht, The Netherlands), Rens van de Goor and colleagues found that recurrent head & neck cancer can be detected using exhaled-breath analysis. They published their findings in an open access paper in Head & Neck
Home / Clinical results / Head and Neck Cancer
Discriminating between head and neck, bladder, and colon carcinomas
Van de Goor RMGE, Leunis N, van Hooren MRA, Francisca E, Masclee A, Kremer B, Kross KW, Feasibility of electronic nose technology for discriminating between head and neck, bladder, and colon carcinomas. Eur Arch Otorhinolaryngol, October 2016.
Aeonose concept study Head and Neck
Head & Neck Cancer calibration study with Aeonose
In Maastricht UMC in cooperation with Dr. K.Kross, we performed a calibration study (32 patients and 26 healthy controls) to assess the diagnostic value of an implementation of a generic electronic nose (Aeonose) using exhaled breath to detect H&N Cancer
In the calibration study we found a sensitivity of 88.5% and a specificity of 87.5% discriminating healthy controls from H&N patients.
This is shown in the ROC-curve drawn below:
Head and Neck Cancer ROC curve
An efficacy study will start soon, led by Dr. K.Kross at Maastricht UMC, and the University hospitals in Groningen (NL), Liege (B) and Turku (Fin).
We will also validate the model by several studies in other university and peripheral hospitals in the Netherlands.